SOME NEW N-SUBSTITUTED ALPHA-ARYL ALKYL SUCCINIMIDES AS POSSIBLE ANTICONVULSANTS

被引：0

作者：

AMIR, M ^{[1
]}

SINGH, E ^{[1
]}

机构：

[1] UNIV LUCKNOW,LUCKNOW 226007,UTTAR PRADESH,INDIA

来源：

PHARMAZIE | 1991年 / 46卷 / 10期

关键词：

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

In view of their expected MAO inhibitory CNS depressant and anticonvulsant properties a number of N-(5-alkyl-1,3,4-thiadiazol-2-yl)-alpha-aryl/alkyl succinimides (1-20) and N-(cyclohexyl)-alpha-aryl/alkyl succinimides (21-25) have been synthesized. Some of them when screened for anticonvulsant activity against pentetrazole induced seizures in mice at a dose of 80 mg/kg were found to be 10 to 50% active.

引用

页码：705 / 707

页数：3

共 50 条

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