PYRROLOBENZODIAZEPINE AND RELATED SYSTEMS .1. SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF NEW 5,6-DIHYDRO-4H-PYRROLO[1,2-A][1,4]BENZODIAZEPINE DERIVATIVES

被引：0
|
作者：
MASSA, S
ARTICO, M
MAI, A
CORELLI, F
PANTALEONI, GC
GIORGI, R
OTTAVIANI, D
CAGNOTTO, A
机构：
[1] UNIV SIENA,DIPARTIMENTO FARMACO CHIM TECNOL,I-53100 SIENA,ITALY
[2] UNIV LAQUILA,CATTEDRA FARMACOL MED,I-67100 LAQUILA,ITALY
[3] MARIO NEGRI INST PHARMACOL RES,I-20157 MILAN,ITALY
来源：
FARMACO | 1990年 / 45卷 / 12期
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Some new 5,6-dihydro-4H-pyrrolo[1,2-a][1,4]benzodiazepine derivatives substitued at the 5 position have been synthesized and tested to evaluate their antidepressant and neuropsychopharmacological activities. The antinociceptic action of these compounds has been also essayed. The introduction of an ethoxycarbonyl group at the 4 position generally decreased the antidepressant effect.
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页码：1265 / 1281
页数：17
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