Erectile Dysfunction and Coronary Artery Disease in Patients with Diabetes

被引:28
|
作者
Gazzaruso, Carmine [1 ,2 ,3 ]
Coppola, Adriana [1 ,2 ]
Giustina, Andrea [4 ]
机构
[1] Hosp Grp San Donato, Internal Med Vasc & Endocrine Metab Dis Unit, ICBM, Vigevano, Italy
[2] Hosp Grp San Donato, Ctr Appl Clin Res Ce RCA, ICBM, Vigevano, Italy
[3] IRCCS Policlin San Donato, Dept Internal Med, San Donato Milanese, Italy
[4] Univ Brescia, Dept Med & Surg Sci, Brescia, Italy
关键词
Diabetes; Erectile dysfunction; Coronary artery disease; Silent myocardial ischemia;
D O I
10.2174/157339911794940693
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The review deals with recent findings regarding the association between erectile dysfunction (ED) and coronary artery disease (CAD) in patients with diabetes. Indeed recent longitudinal studies have shown that ED is able to predict future cardiovascular events not only in nondiabetic but also in diabetic patients. In addition, in diabetic patients ED seems to be strongly associated with the presence of silent CAD. The mechanism by which ED is linked to CAD seems to be the presence of endothelial dysfunction. This pathophysiological mechanism has been extensively analysed. The possible clinical usefulness of ED to identify diabetic patients with silent CAD or at particularly high cardiovascular risk has been discussed in the review. At last, the review reports current guidelines and recent data available in the literature on the treatment of ED in patients with and without CAD and on the prevention of CAD in patients with ED.
引用
收藏
页码:143 / 147
页数:5
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