Comparison of the Efficacy of Standard Interferon Alpha 2a Plus Ribavirin and Pegylated Interferon Alpha 2a Plus Ribavirin Combination Therapies in the Treatment of Chronic Hepatitis C Infection

被引：0
|
作者：
Sumer, Sua [1 ]
Ural, Onur [2 ]
Demir, Nazlim Aktug [3 ]
Ural, Gaye [4 ]
Balci, Mehmet [5 ]
Dikici, Nebahat [2 ]
机构：
[1] Duzici Devlet Hastanesi, Enfeksiyon Hastaliklari Klin Mikrobiyol Klinigi, Osmaniye, Turkey
[2] Selcuk Univ Selcuklu, Tip Fak, Enfeksiyon Hastaliklari Klin Mikrobiyoloji Anabil, Konya, Turkey
[3] Adiyaman Devlet Hastanesi, Enfeksiyon Hastaliklari Klin Mikrobiyol Klinig, Adiyaman, Turkey
[4] Konya Numune Hastanesi, Enfeksiyon Hastaliklari Klin Mikrobiyol Klinigi, Konya, Turkey
[5] Enfeksiyon Hastaliklari Klin Mikrobiyol Klinigi, Hopa Devlet Hastanesi, Artvin, Turkey
来源：
VIRAL HEPATIT DERGISI-VIRAL HEPATITIS JOURNAL | 2009年 / 14卷 / 03期
关键词：
Chronic hepatitis C; standard interferon alpha 2a; pegylated interferon alpha 2a; virological response;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
In the present study, the efficacy of standard interferon alpha 2a plus ribavirin and pegylated interferon alpha 2a plus ribavirin combination therapies were compared in the treatment of 85 patients with chronic hepatitis C (CHC). In standard interferon alpha 2a plus ribavirin group; early virological response (EVR), end treatment virological response (ETR), and sustained virological response (SVR) rates were 69.6%, 66.6% and 42.4%, respectively; while they were 89%, 76% and 53.4% in pegylated interferon alpha 2a plus ribavirin group, respectively. Only EVR rates were statistically different between treatment groups; no significant difference wasobserved between groups in termsof ETR and SVR.
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页码：87 / 90
页数：4
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