L-CARNITINE AS A TREATMENT OF LETHARGY IN CHILDREN WITH CHRONIC NEUROLOGIC HANDICAPS

被引：6
|
作者：
PLIOPLYS, AV
BAGHERPOUR, S
KASNICKA, I
机构：
[1] LITTLE ANGELS NURSING HOME,CHICAGO,IL
[2] MARKLUND CHILDRENS HOME,CHICAGO,IL
[3] UNIV ILLINOIS,DEPT NEUROL,CHICAGO,IL
来源：
BRAIN & DEVELOPMENT | 1994年 / 16卷 / 02期
关键词：
L-CARNITINE; LETHARGY;
D O I：
10.1016/0387-7604(94)90052-3
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
We present five cases of children with severe neurologic handicaps whose management was complicated by excessive lethargy. Treatment with L-carnitine in a dosage range of 35-50 mg/kg/day resulted in a marked improvement in alertness and arousability. In four cases, when L-carnitine was discontinued for a month, they all promptly became lethargic. When L-carnitine was re-started, the lethargy resolved and the improvement has been maintained for up to 14 months. In three children who were tested, serum carnitine levels (total and free) were normal before starting L-carnitine treatment.
引用
收藏
页码：146 / 149
页数：4
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