NEW MATERIALS FOR BIOTECHNOLOGY - CHROMATOGRAPHIC STATIONARY PHASES BASED ON ZIRCONIA

被引：78
|
作者：
NAWROCKI, J
DUNLAP, CJ
CARR, PW
BLACKWELL, JA
机构：
[1] UNIV MINNESOTA, DEPT CHEM, MINNEAPOLIS, MN 55455 USA
[2] THREE M CO, 3M CTR, 3M PHARMACEUT, ANALYT DEV LAB, ST PAUL, MN 55144 USA
[3] ADAM MICKIEWICZ UNIV POZNAN, FAC CHEM, DEPT WATER TREATMENT TECHNOL, PL-60780 POZNAN, POLAND
来源：
BIOTECHNOLOGY PROGRESS | 1994年 / 10卷 / 06期
关键词：
D O I：
10.1021/bp00030a001
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
This review explores the usefulness of zirconia-based materials in separations in biotechnology. The physical and chemical properties of zirconia are discussed briefly to familiarize the reader with the advantages of zirconia. The use of native zirconia is then examined, with a study of the Lewis acid/base chemistry that defines chromatography with zirconia. Modification of the zirconia surface with small molecules is then discussed. Finally; polymer-coated zirconia materials are examined. Examples of separations using these various materials are shown. The advantages and disadvantages of each of these materials are presented.
引用
收藏
页码：561 / 573
页数：13
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