Seasonal variation of stroke incidence in Wujin, a city in southeast China

Objective This study aimed to evaluate seasonal variations in stroke incidence in a city in southeast China. Methods First-ever stroke in residents aged 20 or older in Wujin city was reported by local physicians between January 2006 and December 2007. All reported stroke cases were checked with the city-wide health insurance system. Fatal cases were checked with the household registry system. The annualized stroke incidences were calculated for each month and each season. The stroke incidence was compared among seasons, with spring as a reference. Results Wujin city had an adult (>= 20 y old) population of 1 278 020 in 2010. A total of 2319 stroke cases, 1217 male and 1102 female, were reported in 2006 and 2007. The raw annual incidence of stroke was 90.7/100 000 (95% CI: 82.1-94.5). Stroke incidence was highest in September (125.2/100 000; 95% CI = 109.4-139.3) and lowest in January (78.8/100 000; 95% CI = 69.1-93.2). Stroke incidence was highest in autumn (OR = 1.18, 95% CI: 1.05-1.32, P < .001, compared with spring). Autumn also had the highest incidences of ischemic stroke (OR = 1.22, 95% CI: 1.06-1.40). Conclusions Stroke incidence showed monthly and seasonal variations in southeast China. Autumn had the highest incidences of both ischemic stroke and cerebral hemorrhage.