Current diagnostics and therapy of the most important forms of systemic amyloidosis

Background. Systemic amyloidosis is a rare protein deposition disorder in which diagnosis is often delayed due to the non-specific symptoms at disease onset; however, renal involvement can be detected early during the evaluation of proteinuria. This article gives an overview of current data regarding diagnosis, prognosis and treatment of systemic amyloidosis. Conclusion. The prognosis of this fatal disease has recently improved due to the new diagnostic tools and treatment options; however, early diagnosis plays a crucial role in order to circumvent, e.g. dialysis.