How do Ca2+ ions pass through the sarcoplasmic reticulum membrane

被引:6
|
作者
Mintz, E [1 ]
Guillain, F [1 ]
机构
[1] CENS,DEPT BIOL CELLULAIRE & MOLEC,URA 1290 CNRS,SECT BIOPHYS PROT & MEMBRANES,F-91191 GIF SUR YVETTE,FRANCE
关键词
ATPase; calcium; sarcoplasmic reticulum;
D O I
10.1007/BF01788369
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
We propose an overview of the mechanism of Ca2+ transport through the sarcoplasmic reticulum membrane via the Ca2+-ATPase. We describe cytoplasmic calcium binding, calcium occlusion in the membrane and lumenal calcium dissociation. A channel-like structure is discussed and related to structural data on the membranous domain of the Ca2+-ATPase.
引用
收藏
页码:377 / 385
页数:9
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