IDENTIFICATION OF A NOVEL SECRETED GLYCOPROTEIN OF THE YEAST SACCHAROMYCES-CEREVISIAE STIMULATED BY HEAT-SHOCK

被引：21

作者：

LUPASHIN, VV ^{[1
]}

KONONOVA, SV ^{[1
]}

RATNER, YN ^{[1
]}

TSIOMENKO, AB ^{[1
]}

KULAEV, IS ^{[1
]}

机构：

[1] ACAD SCI USSR,INST BIOCHEM & PHYSIOL MICROORGANISMS,PUSHCHINO 142292,USSR

来源：

YEAST | 1992年 / 8卷 / 03期

关键词：

YEAST; PROTEIN EXPORT; HEAT SHOCK;

D O I：

10.1002/yea.320080302

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A new secreted yeast glycoprotein with an M(r) of about 400 kDa (gp400) has been found. The glycoprotein is an O-mannosylated oligomer, whose synthesis and export into culture medium are stimulated by heat shock. Intracellular transport of gp400 is carried out by membrane vesicles distinct from the known constitutive secretory vesicles. Immunological analysis revealed gp400 only in Saccharomyces species.

引用

页码：157 / 169

页数：13

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