Congenital adrenal hyperplasia - a case report

21-hydroxylase deficiency is the most frequent cause of congenital adrenal hyperplasia (CAH), resulting in a negative feedback in adrenal-hypophysis loop disorder. Excessive ACTH stimulation leads to overproduction of androgens that in female fetus causes virilization. We present a case of a female with classical CAH diagnosed at the age of 4 years. Virilization of genitals - stage 3 according to Prader. Bone age was accelerated (11 years), serum concentrations of testosterone, androstendione, 17-OH progesterone, plasma renin activity as well as aldosterone were elevated. The presented case authorizes us to call for examining of urogenital organs during every visit.