PATHOPHYSIOLOGY AND THERAPY OF GASTRODUODENAL SIDE-EFFECTS OF NONSTEROIDAL ANTIINFLAMMATORY DRUGS

被引：0

作者：

LUBBECKE, F

机构：

来源：

MEDIZINISCHE WELT | 1993年 / 44卷 / 01期

关键词：

ANTIINFLAMMATORY DRUGS; GASTRODUODENAL ULCERS; H-2-RECEPTOR ANTAGONISTS; MISOPROSTOL; OMEPRAZOLE;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The development of gastro-duodenal ulcers is a relevant side effect of treatment with non steroidal anti-inflammatory drugs (NSAID). The diminution in mucosal prostaglandin content in connection with a decreased blood perfusion, which is at least partially a consequence of an increased leucocyte adherence to mesenteric blood vessels, appear to be the pathogenetic key mechanisms. The prostaglandin analogue misoprostol, H-2-receptor antagonists as well as the H+/K+-ATPase inhibitor omeprazole are effective therapeutic agents.

引用

页码：38 / 41

页数：4

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