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SPECIFIC COLLAGEN MESSENGER-RNAS ELUCIDATE THE HISTOGENETIC RELATIONSHIP BETWEEN THE GROWTH-PLATE, THE TISSUE IN THE OSSIFICATION GROOVE OF RANVIER, AND THE CAMBIUM LAYER OF THE ADJACENT PERIOSTEUM - A PRELIMINARY-REPORT
被引：0
|作者：
LANGENSKIOLD, A
ELIMA, K
VUORIO, E
机构：
[1] INVALID FDN,ORTHOPAED RES LAB,HELSINKI,FINLAND
[2] UNIV TURKU,DEPT MED BIOCHEM,SF-20500 TURKU 50,FINLAND
[3] UNIV TURKU,DEPT MOLEC BIOL,SF-20500 TURKU 50,FINLAND
关键词：
D O I：
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中图分类号：
R826.8 [整形外科学];
R782.2 [口腔颌面部整形外科学];
R726.2 [小儿整形外科学];
R62 [整形外科学（修复外科学）];
学科分类号：
摘要：
In situ hybridization was employed to study cellular phenotypes in the ossification groove of Ranvier in young rabbits. The expression of Type II collagen mRNA was seen in chondrocytes in all layers of the growth plate. Messenger RNA for the cartilage-specific Type II collagen was also detected in cells of the inner layer in the ossification groove and of the cambium layer of the adjacent periosteum, providing strong evidence for the views of Ranvier that these cells originate in the growth plate. These findings modify the interpretation of the pathogenesis of diseases of the growing skeleton.
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页码：51 / 54
页数：4
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