SYNTHESIS OF SOME NOVEL FUSED TETRACYCLIC QUINOLONECARBOXYLIC ACIDS VIA 7-METHYL-6,7,8,9-TETRAHYDRO-3H-IMIDAZO[4,5-F]QUINOLINE AND 6-METHYL-5,6,7,8-TETRAHYDRO-1H-IMIDAZO[4,5-G]QUINOLINE

被引：2
|
作者：
LEGOFF, C
BOUYSSOU, P
CHENAULT, J
机构：
[1] Laboratoire de Chimie Bioorganique et Analytique, associé au C.N.R. S, U.R.A. 499, Université d'Orléans, Orléans, F-45067
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 1994年 / 31卷 / 01期
关键词：
D O I：
10.1002/jhet.5570310126
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A series of fused tetracyclic quinolonecarboxylic acids was prepared for biological evaluation. These compounds were synthesized by a route involving a regiospecific functionalization of 5-fluoro-2-methyl-1,2,3,4-tetrahydroquinoline to obtain a series of new substituted 7-methyl-6,7,8,9-tetrahydro-3H-imidazo[4,5-f]quinolines and 6-methyl-5,6,7,8-tetrahydro-1H-imidazo[4,5-g]quinolines as convenient precursors of quinolones.
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收藏
页码：153 / 160
页数：8
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