INVESTIGATION OF PH-SENSITIVE DRUG-DELIVERY SYSTEM OF CHITOSAN/GELATIN HYBRID POLYMER NETWORK

被引：75
|
作者：
YAO, KD
YIN, YJ
XU, MX
WANG, YF
机构：
[1] Research Institute of Polymeric Materials, Tianjin University, Tianjin
来源：
POLYMER INTERNATIONAL | 1995年 / 38卷 / 01期
关键词：
DRUG RELEASE; HYBRID POLYMER NETWORK; CHITOSAN GELATIN; PH-SENSITIVE GEL; SWELLING;
D O I：
10.1002/pi.1995.210380110
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
A novel hydrogel based on a crosslinked chitosan/gelatin with glutaraldehyde hybrid polymer network was prepared. The gel swells in acidic medium and deswells in alkaline medium. A comparative study of the pH-dependent release of levamisole, cimetidine and chloramphenicol was carried out.
引用
收藏
页码：77 / 82
页数：6
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