AN AMINO-TERMINAL FRAGMENT OF SV40 T-ANTIGEN TRANSFORMS REF52 CELLS

被引：19

作者：

SOMPAYRAC, L

DANNA, KJ

机构：

[1] Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder

来源：

VIROLOGY | 1992年 / 191卷 / 01期

关键词：

D O I：

10.1016/0042-6822(92)90206-5

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

An SV40 mutant, T147D, encodes only the amino-terminal 147 amino acids of large T antigen and does not make small t antigen. We show here that a retrovirus which expresses this mutant T antigen transforms rat REF52 cells as efficiently as a retrovirus that expresses both the wild-type large and small T antigens. This cell line had previously been refractory to transformation by mutants that make short, amino-terminal fragments of T antigen. © 1992.

引用

页码：439 / 442

页数：4

共 50 条

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[2] AN AMINO-TERMINAL FRAGMENT OF SV40 T-ANTIGEN INDUCES CELLULAR DNA-SYNTHESIS IN QUIESCENT RAT-CELLS
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[9] PHOSPHORYLATION OF SV40 LARGE T-ANTIGEN
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