A SEROEPIDEMIOLOGICAL SURVEY FOR ORTHOPOX VIRUS IN THE RED FOX (VULPES-VULPES)

被引:16
|
作者
HENNING, K
CZERNY, CP
MEYER, H
MULLER, T
KRAMER, M
机构
[1] WHO,CTR COLLECT DATA & COLLABORAT VIROL,INST MED MICROBIOL INFECT & EPIDEM DIS,D-80539 MUNICH,GERMANY
[2] FED ARMED FORCES MED ACAD,INST MICROBIOL,D-80937 MUNICH,GERMANY
关键词
ORTHOPOX VIRUS; RED FOX; SEROEPIDEMIOLOGY;
D O I
10.1016/0378-1135(94)00097-G
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
703 blood samples from red foxes (Vulpes vulpes) were investigated to determine the prevalence of antibody against an orthopox virus (vaccinia virus strain Elstree). A blocking-ELISA based on a neutralizing monoclonal antibody was used. In this assay 46 sera (6.5%) were positive with titers of 1:2 to 1:16. ELISA-results were confirmed by the plaque reduction test with 44 of the 46 sera reacting positively. The specificity of antibodies in 21 selected sera was also demonstrated by Western blot analysis.
引用
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页码:251 / 259
页数:9
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