PREPARATION OF 2,5-DIMETHYL-3-(2-METHYL-1-CYCLOHEXENYL)-4-THIOPHENECARBOXYLIC ACID AND 2,5-DIMETHYL-3-(2-METHYL-2,6-CYCLOHEXADIENYL)-4-THIOPHENECARBOXYLIC ACID

被引：0
|
作者：
SVENSSON, A
HAKANSSON, R
机构：
来源：
CHEMICA SCRIPTA | 1981年 / 18卷 / 05期
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暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Some presumptively optically active (atropisomeric) thiophene derivatives with a 2-methyl-1-cyclohexenyl group at the 3-position have been prepared by reacting a 3-thienyllithium compound with 2-methylcyclohexanone, followed by the elimination of water from the resulting tertiary alcohol. A method for directing the elimination reaction has been worked out. The title compounds were obtained starting from 3,4-dibromo-2,5-dimethylthiophene and 2-methyl-cyclohexanone and 2-methyl-2-cyclohexenone, respectively.
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页码：202 / 205
页数：4
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