MODEL FOR SOLUBILITY ESTIMATION IN MIXED-SOLVENT SYSTEMS

被引：38
|
作者：
BARZEGARJALALI, M [1 ]
HANAEE, J [1 ]
机构：
[1] TABRIZ UNIV MED SCI,SCH PHARM,DEPT PHARMACEUT CHEM,TABRIZ,IRAN
来源：
INTERNATIONAL JOURNAL OF PHARMACEUTICS | 1994年 / 109卷 / 03期
关键词：
SOLUBILITY ESTIMATION; COSOLVENCY; MIXED SOLVENT SYSTEM; DOUBLE LOG-LOG MODEL; SOLUBILITY DATA LINEARIZATION;
D O I：
10.1016/0378-5173(94)90391-3
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
A simple and rapid method referred to as the double log-log model for linearizing solubility data obtained from mixed solvent systems is presented. The model was able to linearize data which could not be linearized by means of the log-linear solubility equation. Also, the accuracy and prediction capability of the model were greater than those of the excess free energy equation of solubility estimation.
引用
收藏
页码：291 / 295
页数：5
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