Nonfatal Suicidal Overdose of Olanzapine in an Adolescent

被引：6
|
作者：
Singh, Lokesh Kumar [1 ,2 ]
Praharaj, Samir Kumar [3 ]
Sahu, Manoj [1 ,2 ]
机构：
[1] Pandit Jawaharlal Nehru Mem Med Coll, Dept Psychiat, Raipur 492001, Chhattisgarh, India
[2] Dr Bhimrao Ambedkar Mem Hosp, Raipur 492001, Chhattisgarh, India
[3] Kasturba Med Coll & Hosp, Dept Psychiat, Manipal 576104, Karnataka, India
来源：
CURRENT DRUG SAFETY | 2012年 / 7卷 / 04期
关键词：
Olanzapine; overdose; adolescent DSH;
D O I：
10.2174/157488612804096605
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The atypical antipsychotic olanzapine is increasingly being used for various psychiatric conditions. There are few reports of olanzapine overdose in adolescent population. We report a case of 16-year-old adolescent who ingested 750 mg olanzapine, the highest reported nonlethal dose of olanzapine in adolescents. He presented with tachycardia, hypotension, generalized myoclonus, hyperpyrexia, muscular rigidity, leukocytosis and elevated creatine phosphokinase (CPK) levels. He recovered from the toxicity with minimal intervention.
引用
收藏
页码：328 / 329
页数：2
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