Hemophagocytic syndrome and acute pancreatitis in acute systemic lupus erythematosus

被引:0
|
作者
Alblewi, Bushra [1 ,2 ]
Bukhari, Iqbal A. [1 ,2 ]
Hasan, Manal [2 ,3 ]
Alzahani, Abdulaziz [1 ,2 ]
Bukhari, Raed [2 ,3 ]
Bashawri, Layla [2 ,4 ]
Al Shawarby, Muhammad [2 ,4 ]
机构
[1] Univ Dammam, Coll Med, Dermatol Dept, Dammam, Saudi Arabia
[2] King Fahd Hosp Univ, Dammam, Saudi Arabia
[3] Univ Dammam, Coll Med, Internal Med Dept, Dammam, Saudi Arabia
[4] Univ Dammam, Coll Med, Pathol Dept, Dammam, Saudi Arabia
来源
关键词
Hemophagocytic syndrome; Acute systemic lupus erythematosus; Acute pancreatitis;
D O I
10.1016/j.jdds.2014.03.004
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Hemophagocytic syndrome (HPS) is characterized by the activation of histiocytes with prominent hemophagocytosis in bone marrow and other reticuloendothelial systems. It has two forms: primary and secondary. The precise pathogenesis of HPS is unclear but a dysregulation of macrophage-lymphocyte interactions with subsequent increases in the levels of both T-cell-derived and macrophagederived cytokines has been suggested. Cardinal symptoms of HPS are prolonged high fever, hepatosplenomegaly, cytopenias, lymphadenopathy and neurological symptoms. In this report, we present a case Systemic Lupus Erythematosus associated with HPS and acute pancreatitis. (C) 2014 Production and hosting by Elsevier B.V.
引用
收藏
页码:35 / 37
页数:3
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