INTRAVESICAL CHEMOTHERAPY (MITOMYCIN-C) VERSUS IMMUNOTHERAPY (BACILLUS CALMETTE-GUERIN) IN SUPERFICIAL BLADDER-CANCER

被引：1
|
作者：
RINTALA, E [1 ]
JAUHIAINEN, K [1 ]
ALFTHAN, O [1 ]
HANSSON, E [1 ]
JUUSELA, H [1 ]
KANERVA, K [1 ]
KORHONEN, H [1 ]
PERMI, J [1 ]
SOTARAUTA, M [1 ]
VAALASTI, T [1 ]
VIITANEN, J [1 ]
USENIUS, R [1 ]
机构：
[1] UNIV HELSINKI,CENT HOSP,UROL CLIN,FINNBLADDER GRP,SF-00100 HELSINKI 10,FINLAND
来源：
EUROPEAN UROLOGY | 1991年 / 20卷 / 01期
关键词：
INTRAVESICAL THERAPY; SUPERFICIAL BLADDER CANCER; MITOMYCIN-C; BACILLUS CALMETTE-GUERIN;
D O I：
暂无
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Both intravesical mitomycin C (MMC) and bacillus Calmette-Guerin (BCG; Pasteur strain F) were effective in the present prospective randomized multicenter study consisting of 91 patients with frequently recurrent superficial (T(a)-T1) bladder cancer. The result was in favour of BCG, as shown by the measurements with complete response (CR), disease-free inter-val and recurrence rate. CR of 58% with MMC and 40% with BCG were reached in 22 instillation series on carcinoma in situ of 18 patients. Due to side effects, MMC instillations were discontinued in 8.6%, and BCG instillations in 19.6%, respectively. After the 2-year follow-up also 1 case of pulmonary tuberculosis occurred in the BCG group.
引用
收藏
页码：19 / 25
页数：7
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