CHEMOENZYMATIC APPROACH TO THE AB RING-SYSTEM OF AKLAVINONE

被引：25

作者：

GUANTI, G ^{[1
]}

BANFI, L ^{[1
]}

BRUSCO, S ^{[1
]}

RIVA, R ^{[1
]}

机构：

[1] CNR,CTR STUDIO CHIM COMPOSTI CICLOALIFAT & AROMAT,I-16132 GENOA,ITALY

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 52期

关键词：

D O I：

10.1016/S0040-4039(00)61382-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Both enantiomers of compound 3, a possible intermediate for the AB ring system 2 of Aklavinone 1, were obtained in optically active form from diol 7. Key steps were the preparation of both enantiomers of monoacetate 8d, via enzymatic reactions that utilize PPL as catalyst, and the construction of ring A in a totally regioselective manner.

引用

页码：8549 / 8552

页数：4

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