A NOVEL MECHANISM OF RESISTANCE TO METHOTREXATE (MTX) IN HUMAN-BREAST CANCER-CELLS - LACK OF MTX POLYGLUTAMATE FORMATION

被引：0

作者：

COWAN, KH ^{[1
]}

JOLIVET, J ^{[1
]}

机构：

[1] NCI,BETHESDA,MD 20205

来源：

CLINICAL RESEARCH | 1983年 / 31卷 / 02期

关键词：

D O I：

暂无

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

引用

页码：A508 / A508

页数：1

共 50 条

[1] DISTRIBUTION OF METHOTREXATE POLYGLUTAMATES (MTX+GN) IN CULTURED HUMAN-BREAST CANCER-CELLS
SCHILSKY, RL
CHABNER, BA
[J]. PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, 1980, 21 (MAR): : 280 - 280
[2] METHOTREXATE POLYGLUTAMATE SYNTHESIS BY CULTURED HUMAN-BREAST CANCER-CELLS
SCHILSKY, RL
BAILEY, BD
CHABNER, BA
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (05): : 2919 - 2922
[3] INSULIN EFFECTS ON METHOTREXATE POLYGLUTAMATE (MTXGN) SYNTHESIS IN CULTURED HUMAN-BREAST CANCER-CELLS
SCHILSKY, RL
ORDWAY, F
[J]. BREAST CANCER RESEARCH AND TREATMENT, 1983, 3 (03) : 307 - 307
[4] THE REGULATION OF DIHYDROFOLATE-REDUCTASE (DHFR) IN GENE-AMPLIFIED METHOTREXATE (MTX) RESISTANT HUMAN-BREAST CANCER-CELLS
JOLIVET, J
LEVINE, RM
COWAN, KH
[J]. CLINICAL RESEARCH, 1983, 31 (02): : A509 - A509
[5] POLYGLUTAMATE (PG) METABOLITES PROLONG METHOTREXATE (MTX) ACTION IN BREAST-CANCER CELLS
JOLIVET, J
SCHILSKY, RL
BAILEY, BD
DRAKE, JC
CHABNER, BA
[J]. PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, 1982, 23 (MAR): : 179 - 179
[6] POTENTIATION OF THE CYTOTOXICITY OF SEQUENTIAL METHOTREXATE (MTX) 5 FLUOROURACIL (FURA) BY DIPYRIDAMOLE (DP) IN HUMAN-BREAST CANCER-CELLS (MCF 7)
LINDQUIST, CA
CADMAN, E
[J]. PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, 1986, 27 : 299 - 299
[7] INSULIN EFFECTS ON METHOTREXATE POLYGLUTAMATE SYNTHESIS AND ENZYME BINDING IN CULTURED HUMAN-BREAST CANCER-CELLS
SCHILSKY, RL
ORDWAY, FS
[J]. CANCER CHEMOTHERAPY AND PHARMACOLOGY, 1985, 15 (03) : 272 - 277
[8] ESTABLISHMENT OF METHOTREXATE (MTX)-RESISTANT K562 CELL-LINES - IMPAIRMENT OF MTX-POLYGLUTAMATE FORMATION AS A POSSIBLE MECHANISM OF RESISTANCE
KOIZUMI, S
[J]. MEDICAL AND PEDIATRIC ONCOLOGY, 1988, 16 (06): : 434 - 435
[9] INSULIN (I) AUGMENTS METHOTREXATE POLYGLUTAMATE (MTXGN) SYNTHESIS AND ENZYME BINDING IN HUMAN-BREAST CANCER-CELLS
SCHILSKY, RL
ORDWAY, F
[J]. PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, 1984, 25 (MAR): : 309 - 309
[10] THE KINETICS OF METHOTREXATE POLYGLUTAMATION IN HUMAN-BREAST CANCER-CELLS
MORRISON, PF
ALLEGRA, CJ
[J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1987, 254 (02) : 597 - 610

← 1 2 3 4 5 →