IMMUNOHISTOCHEMICAL ANALYSIS OF SALIVARY-GLAND CANILICULAR ADENOMA

被引：20
|
作者：
FERREIRO, JA
机构：
[1] Department of Laboratory Medicine and Pathology, Mayo Clinic. Rochester, MN
来源：
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY | 1994年 / 78卷 / 06期
关键词：
D O I：
10.1016/0030-4220(94)90093-0
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
Canalicular adenoma is a newly recognized salivary gland adenoma that may be confused with malignant salivary gland tumors. To better characterize this neoplasm, six examples were investigated with a panel of immunohistochemistry antibodies including anti-keratin (AE1/AE3), anti-epithelial membrane antigen, anti-carcinoembryonic antigen, anti-vimentin, anti-S-100, anti-muscle specific actin, and anti-glial fibrillary acid protein. All canalicular adenomas stained in a similar fashion showing positive staining with anti-keratin, anti-vimentin, and anti-S-100 (6 of 6 cases each). Rare focal staining with anti-epithelial membrane antigen and anti-glial fibrillary acid protein was noted (1 of 6 cases each). This immunohistochemistry staining pattern was compared with those of ameloblastoma, polymorphous low-grade adenocarcinoma, and adenoid cystic carcinoma. Immunohistochemistry may be useful in the distinction of canalicular adenoma from other salivary gland tumors.
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页码：761 / 765
页数：5
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