RECENT ADVANCES IN THE TREATMENT OF ADVANCED COLORECTAL-CANCER

被引：0
|
作者：
KEMENY, N
LOKICH, JJ
ANDERSON, N
AHLGREN, JD
机构：
[1] CANC CTR BOSTON,BOSTON,MA
[2] GEORGE WASHINGTON UNIV,MED CTR,WASHINGTON,DC 20037
来源：
CANCER | 1993年 / 71卷 / 01期
关键词：
COLORECTAL CANCER; BIOCHEMICAL MODULATION; INTRAHEPATIC AND SYSTEMIC INFUSION;
D O I：
10.1002/1097-0142(19930101)71:1<9::AID-CNCR2820710104>3.0.CO;2-Y
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The treatment of advanced colorectal cancer has improved in recent years. Prospective randomized trials comparing innovative therapies with the ''standard'' bolus dose of 5-fluorouracil (5-FU) found increased response rates after biochemical modification of the drug, infusion administration of 5-FU, and direct intrahepatic arterial infusion. Although the impact on survival of these techniques has been minimal, it is possible that these innovative approaches provide an incremental survival advantage for certain subgroups of patients that may be the foundation for additional therapeutic improvements in the future.
引用
收藏
页码：9 / 18
页数：10
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