Treatment of Latent Tuberculosis Infection in Children

被引:18
|
作者
Cruz, Andrea T. [1 ,2 ,3 ]
Ahmed, Amina [5 ]
Mandalakas, Anna M. [1 ,4 ]
Starke, Jeffrey R. [1 ,2 ]
机构
[1] Texas Childrens Hosp, TB Initiat, Houston, TX 77030 USA
[2] Baylor Coll Med, Dept Pediat, Sect Infectious Dis, Houston, TX 77030 USA
[3] Baylor Coll Med, Dept Pediat, Sect Emergency Med, Houston, TX 77030 USA
[4] Baylor Coll Med, Dept Pediat, Sect Retrovirol, Houston, TX 77030 USA
[5] Carolinas Med Ctr, Dept Pediat, Div Infect Dis, Charlotte, NC 28203 USA
关键词
Latent Tuberculosis Infection; Directly Observed Preventive Therapy; Adherence;
D O I
10.1093/jpids/pit030
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Treatment of latent tuberculosis infection (LTBI) is an effective way of preventing future cases of tuberculosis disease. We review pediatric and adult studies of LTBI treatment (isoniazid and rifampin monotherapy, isoniazid plus rifampin, isoniazid plus rifapentine, and rifampin plus pyrazinamide). Based upon this review and our pediatric experience, we can offer recommendations for routine (isoniazid) and alternative courses of therapy.
引用
收藏
页码:248 / 258
页数:11
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