OLFACTORY SENSITIVITY IN MAJOR DEPRESSIVE DISORDER AND OBSESSIVE-COMPULSIVE DISORDER

被引：69
|
作者：
GROSSISSEROFF, R
LUCAHAIMOVICI, K
SASSON, Y
KINDLER, S
KOTLER, M
ZOHAR, J
机构：
[1] Division of Psychiatry, The Chaim Sheba Medical Center, Tel Hashomer
来源：
BIOLOGICAL PSYCHIATRY | 1994年 / 35卷 / 10期
关键词：
OLFACTORY THRESHOLDS; OBSESSIVE COMPULSIVE DISORDER; MAJOR DEPRESSIVE DISORDER; ISOAMYL ACETATE; ANDROSTENONE;
D O I：
10.1016/0006-3223(94)91142-8
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Olfactory sensitivity to two odorants, isoamyl acetate and androstenone, was assessed in 14 obsessive compulsive disorder (OCD) patients, nine major depressive disorder (MDD) patients, and 16 sex- and age-matched healthy controls. Tests were performed during a drug-free period, and 3 and 6 weeks after initiation of antidepressant drug therapy. No difference in olfactory sensitivity, to either odorant, was found between OCD patients and controls at any time. In MDD patients, a significant increase in the sensitivity to isoamyl acetate was observed 6 weeks after initiation of treatment, compared to controls.
引用
收藏
页码：798 / 802
页数：5
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