IN VITRO FREE RADICAL SCAVENGING ACTIVITY AND SECONDARY METABOLITES IN PASSIFLORA FOETIDA L

Investigation of the total phenol content, total flavanoid content, in vitro lipid peroxidation and radical scavenging activities from Passiflora foetida L. Extraction from various solvents were used for the estimations. Among the five extracts, the flavanoid and phenol content was found to be high in aqueous and ethanol extract of leaf when compared to root extract. Different concentrations of plant extracts were used (100-500 mu g/ml) and results showed strong reducing power at the concentration of 500 mu g/ml and the activity increases in dose dependent manner as to that of standard BHT. That the highest free radical scavenging activity was found in ethanolic extract of leaf of Passiflora foetida L. Consumption of P. foetida L. will reduce the free radical formation and afford protection against reactive oxygen species produced during diabetes which may be due to the presence of phenol and flavanoids.