THE EFFECTS OF CLONIDINE AND 3 2-IMIDAZOLINE DERIVATIVES ON THE SECRETION OF PROTEIN AND SOME ELECTROLYTES BY RAT SUBMANDIBULAR AND PAROTID-GLANDS

被引:9
|
作者
SHIBAIKE, S [1 ]
ABE, K [1 ]
OKINA, A [1 ]
NISHIURA, T [1 ]
机构
[1] FUKUOKA DENT COLL, DEPT ORAL BIOCHEM, FUKUOKA 81401, JAPAN
关键词
D O I
10.1016/0742-8413(92)90085-L
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
1. Three imidazoline analogues of clonidine were potent secretagogues for the 2. Salivation in response to clonidine was completely abolished by prazosin, phentolamine, phenoxybenzamine and dihydroergotamine. 3. The gamma-type of proteins was secreted in response to three of the analogues, whereas with p-aminoclonidine the alpha-type of proteins was secreted by the submandibular gland. 4. Albumin was specifically secreted by the submandibular gland in response to clonidine but not to isoproterenol or phenylephrine.
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页码:547 / 556
页数:10
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