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MODELING MARGINAL HAZARDS IN MULTIVARIATE FAILURE TIME DATA
被引:0
|作者:
LIANG, KY
[1
]
SELF, SG
[1
]
CHANG, YC
[1
]
机构:
[1] FRED HUTCHINSON CANC RES CTR,SEATTLE,WA 98104
来源:
关键词:
FAILURE TIME DATA;
MARGINAL HAZARD;
MULTIVARIATE ANALYSIS;
U-STATISTICS;
D O I:
暂无
中图分类号:
O21 [概率论与数理统计];
C8 [统计学];
学科分类号:
020208 ;
070103 ;
0714 ;
摘要:
We consider the problem of estimating relative risk parameters in the marginal distribution of failure times from a sample in which individuals are grouped into clusters and failure times for individuals within clusters may be dependent. We assume that the marginal hazard of failure for individuals within a cluster is specified by a relative risk regression model and the structure of dependence between individuals within a cluster is left unspecified. Estimating equations for the regression parameters and an estimator for the cumulative base-line marginal hazard are described. Large sample distribution theory based on a representation of the estimating functions as U-statistics is developed and results from a small simulation study are described. Two examples which originally motivated this work are presented.
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页码:441 / 453
页数:13
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