LEVEL OF TOTAL IMMUNOGLOBULIN-E OF THE BLOOD-SERUM OF PATIENTS WITH RHEUMATISM

The mean level of total IgE in the sera of patients with active rheumatism was significantly higher than during non-active phase of the disease and in healthy blood donors. The highest level of hyper-IgE-emia is observed in the continuously relapsing variant of rheumatism. Increased content of total serum IgE in active rheumatism is observed both in manifest and in latent variants of the disease. Articular and cerebral manifestations of rheumatism are not, apparently, related to the IgE level. The serum Ig E may be a supplementary diagnostic criterion of rheumatic activity, especially with advance of the cardiovascular insufficiency.