AQUATIC TOXICOLOGY OF ALKYL-QUINOLINES

Isoquinoline, 2-methyl-8-ethylquinoline, 3-isopropylquinoline, 3-ethylquinoline, three isomers of methylquinoline and fourteen isomers of dimethylquinoline were subjected to toxicity testing using luminescent bacteria (Photobacterium phosphoreum). Toxicity values (effective concentrations of the toxic substance that causes a 50% light reduction-EC50) were determined 5 and 15 min after exposure. Toxicity values were observed to differ by two orders of magnitude and varied according to the degree of substitution and molecular structure. Static 48-h LC50 fish bioassays (Salmo gairdneri) were conducted for three isomers of dimethylquinoline. Good correlation was observed between the fish 48-h LC50 and the bacteria EC50. © 1990.