SELF-REPORTED DEPRESSIVE SYMPTOMS IN ASSOCIATION WITH MEDICATION EXPOSURES AMONG MEDICAL INPATIENTS - A CROSS-SECTIONAL STUDY

被引:0
|
作者
PATTEN, SB [1 ]
WILLIAMS, JVA [1 ]
LOVE, EJ [1 ]
机构
[1] UNIV CALGARY, FAC MED, DEPT PSYCHIAT, CALGARY, AB, CANADA
关键词
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中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Objective: To evaluate associations between exposure to three classes of medications (angiotensin converting enzyme inhibitors, calcium channel blockers, and corticosteroids) and self-reported depressive symptoms. Method: The study utilised a cross-sectional study design in a sample of medical inpatients. Results: Associations between self-reported depressive symptoms and exposure to angiotensin converting enzyme inhibitors or calcium channel blockers were not observed. However, an association between self-reported depressive symptoms and corticosteroid exposure was identified. The association was strongest in subjects reporting a past history of depression or a family history of depression. The strength of the corticosteroid-depressive symptom association was comparable with that of associations observed for age, poverty and psychosocial stress. Conclusions: Depressive symptoms among medical inpatients have a biopsychosocial etiology. Corticosteroid exposure may be a biological risk factor for depressive symptoms in this population.
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页码:264 / 269
页数:6
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