Intravascular device-related infections (IVDRIs) are among the most common nosocomial infections in critically ill patients. Quantitative or semi-quantitative microbiology diagnosis is necessary for their management. Most causative organisms arise from the skin; staphylococci are responsible for two-thirds of the IVDRIs, with Staphylococcus aureus responsible for 5% to 15%. Complications map include septic shock, suppurative thrombophlebitis, and endocarditis. In critically ill patients, intravenous lines are responsible for at least 23% of nosocomial bloodstream infection, which has a mortality of 25% and is associated with a longer stay in intensive care and costs $28,960 per survivor. IVDRls can be treated with intravenous antibiotics without removing the device, but removal of the catheter is recommended. Prevention is based on careful insertion practice and optimal catheter care. Systemic replacement of the intravenous lines every three to five days is common practice in the USA but not elsewhere in Europe. This issue should be studied, particularly in critically ill patients.
机构:
University of Tennessee Medical Center at Knoxville, 1924 Alcoa Highway U-114, Knoxville, 37920-6999, TNUniversity of Tennessee Medical Center at Knoxville, 1924 Alcoa Highway U-114, Knoxville, 37920-6999, TN
Gray N.A.
Baddour L.M.
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机构:
University of Tennessee Medical Center at Knoxville, 1924 Alcoa Highway U-114, Knoxville, 37920-6999, TNUniversity of Tennessee Medical Center at Knoxville, 1924 Alcoa Highway U-114, Knoxville, 37920-6999, TN
机构:
Hop Europeen Georges Pompidou, AP HP, Microbiol Serv, Unite Mobile Microbiol Clin, Paris, France
Univ Paris 05, Paris, FranceInst Pasteur, Dept Microbiol, Unite Genet Biofilms, Paris, France