XENOTRANSPLANTATION - BABOONS AS POTENTIAL LIVER-DONORS - SCIENTIFIC AND ETHICAL ISSUES

被引：0
|
作者：
CHICHE, L [1 ]
ADAM, R [1 ]
CAILLATZUCMAN, S [1 ]
CASTAING, D [1 ]
BACH, JF [1 ]
BISMUTH, H [1 ]
机构：
[1] HOP NECKER ENFANTS MALAD,INSERM,F-75730 PARIS 15,FRANCE
来源：
TRANSPLANTATION | 1993年 / 55卷 / 06期
关键词：
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The dramatic development of liver transplantation compared to a relative shortage of donors has brought a renewed interest to xenotransplantation. Because of anatomical and immunological compatibilities, nonhuman primates are the most appropriate donors. The aim of this work was to analyze the different problems of a baboon-to-man liver xenotransplantation. Thirty baboons bred in a French Primatology Center were studied. The analysis of anatomical, microbiological, and immunological data showed that only 8 baboons out of 30 were suitable as donors for xenotransplantation. Considering these data and the ethical issues, the actual feasibility of xenotransplantation programs is discussed.
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页码：1418 / 1421
页数：4
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