COGNITION IN EPILEPSY - A MULTICHANNEL EVENT RELATED POTENTIAL (P300) STUDY

被引:43
|
作者
TRIANTAFYLLOU, NI [1 ]
ZALONIS, I [1 ]
KOKOTIS, P [1 ]
ANTHRACOPOULOS, M [1 ]
SIAFACAS, A [1 ]
MALLIARA, S [1 ]
HAMBURGER, HL [1 ]
PAPAGEORGIOU, C [1 ]
机构
[1] MUNICIPAL HOSP,DEPT CLIN NEUROPHYSIOL,AMSTERDAM,NETHERLANDS
来源
ACTA NEUROLOGICA SCANDINAVICA | 1992年 / 86卷 / 05期
关键词
COGNITION; P300; AUDITORY EVENT-RELATED POTENTIALS; EVOKED POTENTIALS; EPILEPSY; ANTICONVULSANTS;
D O I
10.1111/j.1600-0404.1992.tb05124.x
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Auditory event-related potentials (AERP) were elicited in 68 epileptic patients and 30 age-matched controls. Epileptic patients had significantly prolonged N2 and P300 (P3) latencies compared with controls. Seven patients were above the range of 3 standard deviations from the control mean values. Amongst epileptics, patients with temporal lobe epilepsy had significantly prolonged P3 latencies compared to patients with idiopathic generalized epilepsy. Patients with abnormal EEGs had significantly prolonged P3 latencies compared to those with normal EEGs. Patients on anticonvulsant monotherapy had shorter P3 latencies, compared to patients taking a combination of two or more anticonvulsants. Patients on shorter duration of treatment had less prolonged P3 latencies compared to those on longer anticonvulsant treatment.
引用
收藏
页码:462 / 465
页数:4
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