COMPARATIVE ACTIVITY OF AMPICILLIN, AMOXICILLIN, AMOXYCILLIN/CLAVULANATE AND CEFOTAXIME AGAINST 189 PENICILLIN-SUSCEPTIBLE AND PENICILLIN-RESISTANT PNEUMOCOCCI

被引：45
|
作者：
PANKUCH, GA
JACOBS, MR
APPELBAUM, PC
机构：
[1] PENN STATE UNIV, MILTON S HERSHEY MED CTR, DEPT PATHOL CLIN MICROBIOL, HERSHEY, PA 17033 USA
[2] CASE WESTERN RESERVE UNIV, INST PATHOL CLIN MICROBIOL, CLEVELAND, OH 44106 USA
来源：
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 1995年 / 35卷 / 06期
关键词：
D O I：
10.1093/jac/35.6.883
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Agar dilution and E-test MICs of penicillin G, ampicillin, amoxycillin, amoxycillin/ clavulanate and cefotaxime were determined against 189 pneumococci. Addition of clavulanate did not influence amoxycillin MICs, MIC(50)/MIC(90) (mg/L) for penicillin G, ampicillin, amoxycillin and cefotaxime were: Penicillin susceptible strains (62): 0.03/0.03; 0.03/0.06; 0.015/0.03; 0.015/0.06. Penicillin intermediate strains (69): 0.25/1.0; 0.25/4.0; 0.125/1.0; 0.125/1.0. Penicillin resistant strains (58): 2.0/4.0; 4.0/4.0;1.0/2.0; 1.0/2.0. E-test MICs correlated well with those obtained by agar dilution.
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页码：883 / 888
页数：6
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