ASSESSMENT OF PLATELET CYTOSOLIC CONCENTRATION OF FREE MAGNESIUM IN HEALTHY-SUBJECTS

被引：0

作者：

YOSHIMURA, M ^{[1
]}

OSHIMA, T ^{[1
]}

MATSUURA, H ^{[1
]}

WATANABE, M ^{[1
]}

HIGASHI, Y ^{[1
]}

ONO, N ^{[1
]}

HIRAGA, H ^{[1
]}

KANBE, M ^{[1
]}

KAJIYAMA, G ^{[1
]}

机构：

[1] HIROSHIMA UNIV,SCH MED,DEPT CLIN LAB MED,HIROSHIMA 734,JAPAN

来源：

JOURNAL OF LABORATORY AND CLINICAL MEDICINE | 1995年 / 125卷 / 06期

关键词：

D O I：

暂无

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

We measured basal cytosolic concentration of free Mg2+ ([Mg2+](i)) in platelets from 30 healthy volunteers by using mag-fura-2, a new fluorescent Mg2+ indicator. The mean [Mg2+](i) was 381 +/- 22 mu mol/L, with values ranging from 226 to 771 mu mol/L. The day-to-day intrasubject coefficient of variation was relatively small (3.6%). [Mg2+](i) was significantly higher in men than in women (430 +/- 38 vs 332 +/- 17 mu mol/L, p < 0.03), and was not correlated with age. There was no significant relation between platelet [Mg2+](i) and serum total Mg concentration. The results indicate that the gender but not age may decide intracellular Mg2+ status. In addition, the mechanisms that regulate [Mg2+](i) may be independent of those that influence the extracellular concentration of Mg.

引用

页码：743 / 747

页数：5

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