SELECTIVE DOPAMINE TRANSPORTER INHIBITION BY COCAINE ANALOGS

被引：56
|
作者：
BOJA, JW
MCNEILL, RM
LEWIN, AH
ABRAHAM, P
CARROLL, FI
KUHAR, MJ
机构：
[1] NIDA,ADDICT RES CTR,NEUROSCI BRANCH,MOLEC PHARMACOL LAB,POB 5180,BALTIMORE,MD 21224
[2] RES TRIANGLE INST,DEPT ORGAN & MED CHEM,RES TRIANGLE PK,NC 27709
来源：
NEUROREPORT | 1992年 / 3卷 / 11期
关键词：
DOPAMINE TRANSPORTER; DOPAMINE UPTAKE; COCAINE; RTI-55;
D O I：
10.1097/00001756-199211000-00009
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
SEVERAL isopropyl and phenyl esters of 3beta-(4-substituted phenyl) tropan-2beta-carboxylic acid analogs of cocaine are relatively more potent and selective than cocaine and some other compounds in inhibiting dopamine uptake. These analogs can be used as binding ligands and as tools for elucidating the mechanisms of action of cocaine.
引用
收藏
页码：984 / 986
页数：3
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