A NEW FACILE ONE-POT PREPARATION OF PENTAFLUOROPHENYL (PFP) AND 3,4-DIHYDRO-4-OXO-1,2,3-BENZOTRIAZINE-3-YL (DHBT) ESTERS OF FMOC AMINO-ACIDS

被引：0

作者：

JAKOBSEN, MH ^{[1
]}

BUCHARDT, O ^{[1
]}

ENGDAHL, T ^{[1
]}

HOLM, A ^{[1
]}

机构：

[1] ROYAL VET & AGR UNIV,DEPT CHEM,CTR MED BIOTECHNOL,DK-1871 COPENHAGEN,DENMARK

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 43期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new one-pot procedure for the preparation of pentafluorophenyl and 3,4-dihydro-4-oxo-1,2,3-benzotriazine-3-yl esters of N-alpha-9-fluorenylmethyloxycarbonyl amino acids bearing no side chain protecting groups is described. The method gives the desired activated esters in high yield and purity without use of the highly allergenic DCC.

引用

页码：6199 / 6202

页数：4

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