Background. Ocular involvement in mycosis fungoides (MF) cases occurs in one-third of patients with the eyelid being the most frequent site affected; however, conjunctival involvement is rarely reported. Herein, we report a rare case of conjunctival involvement of MF. Case Presentation. A 66-year-old man who was previously diagnosed with MF in 2010 and was treated presented in 2014 complaining of foreign body sensation and redness in both eyes. Slit lamp examination of both eyes showed erythematous conjunctival growth that extended circumferentially. Physical examination revealed erythematous skin lesions on different body parts. Conjunctival biopsy was performed and revealed a dense, highly polymorphic lymphocytic population. The immunophenotype demonstrated a neoplastic T-cell origin consistent with MF. A diagnosis of conjunctival involvement by MF was made. The conjunctiva was treated with radiotherapy resulting in tumor regression. There were no recurrences at the 6-month follow-up. Conclusion. T-cell lymphoma should be considered in patients with a history of MF presenting with conjunctival and skin lesions.
机构:
Rabin Med Ctr, Dept Dermatol, Petah Tiqwa, Israel
Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, IsraelRabin Med Ctr, Dept Dermatol, Petah Tiqwa, Israel
Hodak, Emmilia
Amitay-Laish, Iris
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Rabin Med Ctr, Dept Dermatol, Petah Tiqwa, IsraelRabin Med Ctr, Dept Dermatol, Petah Tiqwa, Israel
Amitay-Laish, Iris
Feinmesser, Meora
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Rabin Med Ctr, Dept Pathol, Petah Tiqwa, Israel
Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, IsraelRabin Med Ctr, Dept Dermatol, Petah Tiqwa, Israel
Feinmesser, Meora
Davidovici, Batya
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Rabin Med Ctr, Dept Dermatol, Petah Tiqwa, IsraelRabin Med Ctr, Dept Dermatol, Petah Tiqwa, Israel
Davidovici, Batya
David, Michael
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Rabin Med Ctr, Dept Dermatol, Petah Tiqwa, Israel
Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, IsraelRabin Med Ctr, Dept Dermatol, Petah Tiqwa, Israel
David, Michael
Zvulunov, Alex
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Schneider Childrens Med Ctr Israel, Unit Pediat Dermatol, Petah Tiqwa, Israel
Ben Gurion Univ Negev, Fac Hlth Sci, Med Sch Int Hlth, IL-84105 Beer Sheva, IsraelRabin Med Ctr, Dept Dermatol, Petah Tiqwa, Israel
Zvulunov, Alex
Pavlotsky, Felix
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Sheba Med Ctr, Dept Dermatol, Ramat Gan, Israel
Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, IsraelRabin Med Ctr, Dept Dermatol, Petah Tiqwa, Israel
Pavlotsky, Felix
Yaniv, Isaac
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Schneider Childrens Med Ctr Israel, Dept Pediat Hematol Oncol, Petah Tiqwa, Israel
Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, IsraelRabin Med Ctr, Dept Dermatol, Petah Tiqwa, Israel
Yaniv, Isaac
Avrahami, Gali
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Schneider Childrens Med Ctr Israel, Dept Pediat Hematol Oncol, Petah Tiqwa, Israel
Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, IsraelRabin Med Ctr, Dept Dermatol, Petah Tiqwa, Israel
Avrahami, Gali
Ben-Amitai, Dan
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Schneider Childrens Med Ctr Israel, Unit Pediat Dermatol, Petah Tiqwa, Israel
Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, IsraelRabin Med Ctr, Dept Dermatol, Petah Tiqwa, Israel
机构:
Magna Graecia Univ Catanzaro, Dept Hlth Sci, Viale Europa Loc, I-88100 Catanzaro, ItalyMagna Graecia Univ Catanzaro, Dept Hlth Sci, Viale Europa Loc, I-88100 Catanzaro, Italy
Scali, Elisabetta
Presta, Ivan
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Magna Graecia Univ Catanzaro, Dept Hlth Sci, Viale Europa Loc, I-88100 Catanzaro, ItalyMagna Graecia Univ Catanzaro, Dept Hlth Sci, Viale Europa Loc, I-88100 Catanzaro, Italy
Presta, Ivan
Donato, Annalidia
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Magna Graecia Univ Catanzaro, Dept Med & Surg Sci, I-88100 Catanzaro, ItalyMagna Graecia Univ Catanzaro, Dept Hlth Sci, Viale Europa Loc, I-88100 Catanzaro, Italy
Donato, Annalidia
Schipani, Giusy
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Magna Graecia Univ Catanzaro, Dept Hlth Sci, Viale Europa Loc, I-88100 Catanzaro, ItalyMagna Graecia Univ Catanzaro, Dept Hlth Sci, Viale Europa Loc, I-88100 Catanzaro, Italy
Schipani, Giusy
Dastoli, Stefano
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Magna Graecia Univ Catanzaro, Dept Hlth Sci, Viale Europa Loc, I-88100 Catanzaro, ItalyMagna Graecia Univ Catanzaro, Dept Hlth Sci, Viale Europa Loc, I-88100 Catanzaro, Italy
Dastoli, Stefano
Rossi, Marco
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Magna Graecia Univ Catanzaro, Dept Clin & Expt Med, I-88100 Catanzaro, ItalyMagna Graecia Univ Catanzaro, Dept Hlth Sci, Viale Europa Loc, I-88100 Catanzaro, Italy
Rossi, Marco
Mignogna, Chiara
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Magna Graecia Univ Catanzaro, Dept Interdipartimental Serv Ctr CIS, I-88100 Catanzaro, ItalyMagna Graecia Univ Catanzaro, Dept Hlth Sci, Viale Europa Loc, I-88100 Catanzaro, Italy
Mignogna, Chiara
Malara, Natalia
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Magna Graecia Univ Catanzaro, Dept Clin & Expt Med, I-88100 Catanzaro, ItalyMagna Graecia Univ Catanzaro, Dept Hlth Sci, Viale Europa Loc, I-88100 Catanzaro, Italy
Malara, Natalia
Nistico, Steven Paul
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Magna Graecia Univ Catanzaro, Dept Hlth Sci, Viale Europa Loc, I-88100 Catanzaro, ItalyMagna Graecia Univ Catanzaro, Dept Hlth Sci, Viale Europa Loc, I-88100 Catanzaro, Italy
Nistico, Steven Paul
Donato, Giuseppe
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Magna Graecia Univ Catanzaro, Dept Hlth Sci, Viale Europa Loc, I-88100 Catanzaro, ItalyMagna Graecia Univ Catanzaro, Dept Hlth Sci, Viale Europa Loc, I-88100 Catanzaro, Italy