INHIBITION OF THROMBOXANE-A(2) BIOSYNTHESIS IN-VITRO BY THE MAIN COMPONENTS OF CRATAEGUS-OXYACANTHA (HAWTHORN) FLOWER HEADS

被引：38

作者：

VIBES, J ^{[1
]}

LASSERRE, B ^{[1
]}

GLEYE, J ^{[1
]}

DECLUME, C ^{[1
]}

机构：

[1] CNRS,INST PHYSIOL,2 RUE MAGENDIE,F-31400 TOULOUSE,FRANCE

来源：

PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS | 1994年 / 50卷 / 04期

关键词：

D O I：

10.1016/0952-3278(94)90141-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A hydro-alcoholic extract from Crataegus o. (Co) flower heads inhibited thromboxane A2 (TXA2) biosynthesis in vitro. This present study aims to find out which are the active principles. The main components, as revealed by chromatography, were tested. We also took into consideration catechin and epicatechin: although they do not appear as such with chromatography because of their polymerisation or-and condensed structure, these two proanthocyanidins seem to play a major role in the mentioned activity of the plant.

引用

页码：173 / 175

页数：3