IDENTIFICATION OF A CLASS OF COMPOUNDS THAT BLOCK GP120 BINDING TO CD4 AND SUPPRESS HIV-1 INFECTION IN-VITRO

被引：0
|
作者：
PROFY, AT
PALLAI, PV
NEIDHARDT, EA
SINGH, SK
VANSCHRAVENDIJK, MR
WU, J
WILLIS, KJ
GORDON, K
SAMPO, TM
OSBURNE, MS
RUSCONI, S
MERRIL, D
MOONIS, M
HIRSCH, MS
BUCKHEIT, RW
WORTEL, CH
JENSON, JC
机构：
[1] PROCEPT INC,CAMBRIDGE,ENGLAND
[2] FREDERICK RES CTR,SO RES INST,FREDERICK,MD
[3] MASSACHUSETTS GEN HOSP,BOSTON,MA 02114
来源：
AIDS RESEARCH AND HUMAN RETROVIRUSES | 1995年 / 11卷
关键词：
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
引用
收藏
页码：S169 / S169
页数：1
相关论文
共 50 条
  • [1] α-defensins block the early steps of HIV-1 infection:: interference with the binding of gp120 to CD4
    Furci, Lucinda
    Sironi, Francesca
    Tolazzi, Monica
    Vassena, Lia
    Lusso, Paolo
    BLOOD, 2007, 109 (07) : 2928 - 2935
  • [2] PREVENTION OF HIV-1 INFECTION AND PRESERVATION OF CD4 FUNCTION BY THE BINDING OF CPFS TO GP120
    FINBERG, RW
    DIAMOND, DC
    MITCHELL, DB
    ROSENSTEIN, Y
    SOMAN, G
    NORMAN, TC
    SCHREIBER, SL
    BURAKOFF, SJ
    SCIENCE, 1990, 249 (4966) : 287 - 291
  • [3] PHOSPHOROTHIOATE OLIGODEOXYCYTIDINE INTERFERES WITH BINDING OF HIV-1 GP120 TO CD4
    STEIN, CA
    NECKERS, LM
    NAIR, BC
    MUMBAUER, S
    HOKE, G
    PAL, R
    JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 1991, 4 (07) : 686 - 693
  • [4] IDENTIFICATION OF HUMAN CD4 RESIDUES AFFECTING CLASS-II MHC VERSUS HIV-1 GP120 BINDING
    CLAYTON, LK
    SIEH, M
    PIOUS, DA
    REINHERZ, EL
    NATURE, 1989, 339 (6225) : 548 - 551
  • [5] Binding of full-length HIV-1 gp120 to CD4 induces structural reorientation around the gp120 core
    Ashish
    Garg, Renu
    Anguita, Juan
    Krueger, Joanna K.
    BIOPHYSICAL JOURNAL, 2006, 91 (06) : L69 - L71
  • [6] Molecular mechanism of HIV-1 gp120 mutations that reduce CD4 binding affinity
    Kassler, Kristin
    Sticht, Heinrich
    JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2014, 32 (01): : 52 - 64
  • [7] Scaffolded peptides for the mimicry of the discontinuous CD4 binding site of HIV-1 gp120
    Franke, Raimo
    Hirsch, Tatjana
    Eichler, Jutta
    Peptides 2004, Proceedings: BRIDGES BETWEEN DISCIPLINES, 2005, : 1113 - 1114
  • [8] Synthetic mimetics of the CD4 binding site of HIV-1 gp120 for the design of immunogens
    Franke, Raimo
    Hirsch, Tatjana
    Overwin, Heike
    Eichler, Jutta
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2007, 46 (08) : 1253 - 1255
  • [9] Llama Antibody Fragments that Potently Neutralize HIV-1 at the CD4 Binding Site of HIV-1 Gp120
    McCoy, L.
    Forsman, A.
    Bulmer-Thomas, B.
    Strokappe, N.
    Verrips, T.
    Chen, L.
    Kwong, P. D.
    Weiss, R. A.
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 2011, 27 (10) : A44 - A44
  • [10] BINDING OF SOLUBLE CD4 TO GP120 PROMOTES BINDING OF HIV-1 VIRIONS TO CD4-NEGATIVE CELLS
    DEMARIA, S
    BUSHKIN, Y
    JOURNAL OF CELLULAR BIOCHEMISTRY, 1995, : 218 - 218
12345