UTILITY OF I-123 IMP SPECT BRAIN-SCANS FOR THE EARLY DETECTION OF SITE-SPECIFIC ABNORMALITIES IN CREUTZFELDT-JAKOB-DISEASE (HEIDENHAIN TYPE) - A CASE-STUDY

被引：15

作者：

JIBIKI, I ^{[1
]}

FUKUSHIMA, T ^{[1
]}

KOBAYASHI, K ^{[1
]}

KUROKAWA, K ^{[1
]}

YAMAGUCHI, N ^{[1
]}

MATSUDA, H ^{[1
]}

HISADA, K ^{[1
]}

机构：

[1] KANAZAWA UNIV,SCH MED,DEPT NUCL MED,KANAZAWA,ISHIKAWA 920,JAPAN

来源：

NEUROPSYCHOBIOLOGY | 1994年 / 29卷 / 03期

关键词：

CREUTZFELDT-JAKOB DISEASE (HEIDENHAIN TYPE); I-123 IMP SPECT; REGIONAL CEREBRAL BLOOD FLOW; CORTICAL BLINDNESS;

D O I：

10.1159/000119073

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Serial changes in brain imaging of regional cerebral blood flow with single photon emission computed tomography (SPECT) using N-isopropyl-(iodine-12 3) p-iodoamphetamine (I-123-IMP) were observed in a patient with probable Heidenhain type of Creutzfeldt-Jakob disease, which was characterized by the initial onset of visual symptoms. Corresponding to the visual signs and periodic synchronous discharges localized in the bilateral parietal and occipital regions on EEG, focal hypoperfusion images in the occipital lobes were detected on the SPECT scan before brain X-ray computed tomography and magnetic resonance imaging showed any abnormalities. These results suggest that SPECT brain imaging is useful in the early detection of site-specific abnormalities in Creutzfeldt-Jakob disease.

引用

页码：117 / 119

页数：3

共 3 条

[1] HIGH REPRODUCIBILITY OF REGIONAL ABNORMALITIES ON INTERICTAL I-123 IMP SPECT BRAIN-SCANS IN ADULTS WITH PARTIAL EPILEPSY
JIBIKI, I
KUBOTA, T
FUJIMOTO, K
YAMAGUCHI, N
MATSUDA, H
TSUJI, S
HISADA, K
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE, 1990, 240 (01) : 5 - 8
[2] Brain SPECT with 123I-IMP for the early diagnosis of Creutzfeldt-Jakob disease
Matsuda, M
Tabata, K
Hattori, T
Miki, J
Ikeda, S
JOURNAL OF THE NEUROLOGICAL SCIENCES, 2001, 183 (01) : 5 - 12
[3] ANTAGONIZING CORRELATION BETWEEN PERIODIC SYNCHRONOUS DISCHARGES AND PHOTICALLY INDUCED GIANT EVOKED-RESPONSES IN CREUTZFELDT-JAKOB-DISEASE (HEIDENHAIN TYPE) - A CASE-STUDY
JIBIKI, I
FUKUSHIMA, T
KOBAYASHI, K
AOKI, T
YAMAGUCHI, N
PSYCHIATRY AND CLINICAL NEUROSCIENCES, 1995, 49 (01) : 87 - 90

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