TIME-DEPENDENT CHANGES IN CRF AND ITS MESSENGER-RNA IN THE NEURONS OF THE INFERIOR OLIVE FOLLOWING SURGICAL TRANSECTION OF THE OLIVOCEREBELLAR TRACT IN THE RAT

被引：13

作者：

MEZEY, E ^{[1
]}

PALKOVITS, M ^{[1
]}

机构：

[1] DEPT ANAT 1,BUDAPEST,HUNGARY

来源：

MOLECULAR BRAIN RESEARCH | 1991年 / 10卷 / 01期

关键词：

CORTICOTROPIN-RELEASING FACTOR MESSENGER RNA; INSITU HYBRIDIZATION; CORTICOTROPIN-RELEASING FACTOR IMMUNOCYTOCHEMISTRY; INFERIOR OLIVE; SURGICAL TRANSECTION;

D O I：

10.1016/0169-328X(91)90056-4

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Changes in corticotropin-releasing factor (CRF) immunostaining and CRF mRNA in neurons of the inferior olive were compared following unilateral surgical transections of the olivocerebellar tract. Alterations in CRF immunoreactivity could not be observed earlier than 24 h after surgery. The difference - an accumulation in the contralateral side - was most pronounced at 3 days, and disappeared by the 7th postoperative day. On the other hand, changes in mRNA could be observed as early as 5-30 min after the transection. The most significant accumulation was present at 3 h after the cut and no difference could be observed from the 3rd day following surgery. The results suggest that changes in mRNA levels by axotomy may occur at an earlier time point than previously thought.

引用

页码：55 / 59

页数：5

共 12 条

[1] CHANGES IN CCK MESSENGER-RNA IN HIPPOCAMPAL-NEURONS FOLLOWING FIMBRIA-FORNIX TRANSECTION
PANNI, MK
WILSON, VJ
CAPOOR, U
SOFRONIEW, MV
RATTRAY, M
NEUROREPORT, 1994, 5 (11) : 1377 - 1380
[2] TIME-DEPENDENT CHANGES IN POLYPEPTIDE AND TRANSLATABLE MESSENGER-RNA LEVELS CAUSED BY NACL IN BARLEY ROOTS
ROBINSON, NL
TANAKA, CK
HURKMAN, WJ
PHYSIOLOGIA PLANTARUM, 1990, 78 (01) : 128 - 134
[3] TIME-DEPENDENT EFFECT OF MELATONIN ON ACTIN MESSENGER-RNA LEVELS AND INCORPORATION OF S-35 METHIONINE INTO ACTIN AND PROTEINS BY THE RAT HYPOTHALAMUS
IOVANNA, J
DUSETTI, N
CADENAS, B
CARDINALI, DP
JOURNAL OF PINEAL RESEARCH, 1990, 9 (01) : 51 - 63
[4] SIMILAR TIME COURSE CHANGES IN STRIATAL LEVELS OF GLUTAMIC-ACID DECARBOXYLASE AND PROENKEPHALIN MESSENGER-RNA FOLLOWING DOPAMINERGIC DEAFFERENTATION IN THE RAT
VERNIER, P
JULIEN, JF
RATABOUL, P
FOURRIER, O
FEUERSTEIN, C
MALLET, J
JOURNAL OF NEUROCHEMISTRY, 1988, 51 (05) : 1375 - 1380
[5] PHOTOCHEMICALLY INDUCED FOCAL CEREBRAL-ISCHEMIA IN RAT - TIME-DEPENDENT AND GLOBAL INCREASE IN EXPRESSION OF BASIC FIBROBLAST GROWTH-FACTOR MESSENGER-RNA
LIPPOLDT, A
ANDBJER, B
ROSEN, L
RICHTER, E
GANTEN, D
CAO, Y
PETTERSSON, RF
FUXE, K
BRAIN RESEARCH, 1993, 625 (01) : 45 - 56
[6] TIME-DEPENDENT REGULATION OF RAT ADIPOSE-TISSUE GLUCOSE TRANSPORTER (GLUT4) MESSENGER-RNA AND PROTEIN BY INSULIN IN STREPTOZOCIN-DIABETIC AND NORMAL RATS
SIVITZ, WI
DESAUTEL, SL
LEE, EC
PESSIN, JE
METABOLISM-CLINICAL AND EXPERIMENTAL, 1992, 41 (11): : 1267 - 1272
[7] COMPARISON BETWEEN THE TIME COURSE OF CHANGES IN NERVE GROWTH-FACTOR PROTEIN-LEVELS AND THOSE OF ITS MESSENGER-RNA IN THE CULTURED RAT IRIS
HEUMANN, R
THOENEN, H
JOURNAL OF BIOLOGICAL CHEMISTRY, 1986, 261 (20) : 9246 - 9249
[8] ALTERATIONS OF CA2+/CALMODULIN-DEPENDENT PROTEIN-KINASE-II AND ITS MESSENGER-RNA IN THE RAT HIPPOCAMPUS FOLLOWING NORMOTHERMIC AND HYPOTHERMIC ISCHEMIA
HU, BR
KAMME, F
WIELOCH, T
NEUROSCIENCE, 1995, 68 (04) : 1003 - 1016
[9] TIME-DEPENDENT CHANGES IN ALPHA-1-ADRENOCEPTOR AND BETA-2-ADRENOCEPTOR (ALPHA-1AR AND BETA-2AR) MESSENGER-RNA IN ISOLATED RAT-LIVER CELLS
ISHAC, EJN
LAZARWESLEY, E
SZENTENDREI, T
HADCOCK, JR
MALBON, CC
KUNOS, G
FASEB JOURNAL, 1991, 5 (04): : A513 - A513
[10] GAP-43 MESSENGER-RNA IN RAT SPINAL-CORD AND DORSAL-ROOT GANGLIA NEURONS - DEVELOPMENTAL-CHANGES AND REEXPRESSION FOLLOWING PERIPHERAL-NERVE INJURY
CHONG, MS
FITZGERALD, M
WINTER, J
HUTSAI, M
EMSON, PC
WIESE, U
WOOLF, CJ
EUROPEAN JOURNAL OF NEUROSCIENCE, 1992, 4 (10) : 883 - 895

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