SYNTHESIS AND BIOLOGICAL EVALUATION OF FORSKOLIN CARBAMATES AS POTENTIAL ADENYLYL-CYCLASE ISOFORM SELECTIVE LIGANDS

被引：0
|
作者：
ROBBINS, JD
BORING, DL
TANG, WJ
SHANK, R
SEAMON, KB
机构：
[1] UNIV TEXAS,HLTH SCI CTR,SW MED SCH,DALLAS,TX 75235
[2] US FDA,CTR BIOL EVALUAT & RES,DBB,LMP,BETHESDA,MD 20892
[3] DAVDP,ODE 2,CTR DRUG EVALUAT & RES,ROCKVILLE,MD 20890
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 1994年 / 207卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
引用
收藏
页码：248 / MEDI
相关论文
共 50 条
  • [1] MAPPING OF ADENYLYL-CYCLASE ISOFORM ACTIVATION AND BINDING REQUIREMENTS WITH FORSKOLIN CARBAMATES
    ROBBINS, JD
    BORING, DL
    TANG, WJ
    SHANK, R
    SEAMON, KB
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1994, 208 : 248 - MEDI
  • [2] NOVEL ISOFORM OF ADENYLYL-CYCLASE IN BOVINE CILIARY PROCESSES
    DANIAS, J
    POHORENEC, G
    MITTAG, T
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 1995, 36 (04) : S139 - S139
  • [3] (AMINOALKYL)CARBAMATES OF FORSKOLIN - INTERMEDIATES FOR THE SYNTHESIS OF FUNCTIONALIZED DERIVATIVES OF FORSKOLIN WITH DIFFERENT SPECIFICITIES FOR ADENYLYL CYCLASE AND THE GLUCOSE TRANSPORTER
    ROBBINS, JD
    LAURENZA, A
    KOSLEY, RW
    OMALLEY, GJ
    SPAHL, B
    SEAMON, KB
    JOURNAL OF MEDICINAL CHEMISTRY, 1991, 34 (11) : 3204 - 3212
  • [4] CONSTRUCTION OF A SOLUBLE ADENYLYL-CYCLASE ACTIVATED BY G(S)ALPHA AND FORSKOLIN
    TANG, WJ
    GILMAN, AG
    SCIENCE, 1995, 268 (5218) : 1769 - 1772
  • [5] Forskolin carbamates: Binding and activation studies with type I adenylyl cyclase
    Robbins, JD
    Boring, DL
    Tang, WJ
    Shank, R
    Seamon, KB
    JOURNAL OF MEDICINAL CHEMISTRY, 1996, 39 (14) : 2745 - 2752
  • [6] Characterization of Adenylyl Cyclase Isoform 6 Residues Interacting with Forskolin
    Bhatia, Vikram
    Maghsoudi, Saeid
    Hinton, Martha
    Bhagirath, Anjali Y. Y.
    Singh, Nisha
    Jaggupilli, Appalaraju
    Chelikani, Prashen
    Dakshinamurti, Shyamala
    BIOLOGY-BASEL, 2023, 12 (04):
  • [7] INTERACTION OF AMINOALKYLCARBAMATES OF FORSKOLIN WITH ADENYLYL CYCLASE - SYNTHESIS OF AN IODINATED DERIVATIVE OF FORSKOLIN WITH HIGH-AFFINITY FOR ADENYLYL CYCLASE
    LAURENZA, A
    ROBBINS, JD
    SEAMON, KB
    MOLECULAR PHARMACOLOGY, 1992, 41 (02) : 360 - 368
  • [8] SYNTHESIS OF IODO-ARYL-AZIDO ADENOSINE-ANALOGS AS AFFINITY LIGANDS FOR ADENYLYL-CYCLASE
    SHOSHANI, I
    QIU, H
    JOHNSON, F
    JOHNSON, RA
    NUCLEOSIDES & NUCLEOTIDES, 1994, 13 (09): : 1977 - 1989
  • [9] Synthesis and evaluation of an 18F analog of forskolin for imaging adenylyl cyclase
    Kiesewetter, DO
    Sassaman, MB
    Robbins, J
    Jagoda, EM
    Carson, RE
    Appel, NM
    Sutkowski, E
    Herscovitch, P
    Braun, A
    Eckelman, WC
    JOURNAL OF FLUORINE CHEMISTRY, 2000, 101 (02) : 297 - 304
  • [10] Isoform-selective regulation of adenylyl cyclase by forskolin derivatives: prediction of selectivity by computer-based analysis
    Eguchi, Haruki
    Iwatsubo, Kousaku
    Ishikawa, Yoshihiro
    LETTERS IN DRUG DESIGN & DISCOVERY, 2007, 4 (06) : 434 - 441
12345