SPECTRAL CHARACTERIZATION AND ANTIFUNGAL ACTIVITY OF SOME NEWLY SYNTHESIZED SULFUR-CONTAINING TRIORGANOTIN(IV) DERIVATIVES

Triorganotin(IV) complexes having an azomethine linkage have been prepared by the substitution reactions of trimethyl tin chloride with heterocyclic thiosemicarbazones and characterized by elemental analyses, molecular weight determinations and conductivity measurements. On the basis of infrared, 1H, 13C and119Sn NMR spectroscopy studies, a trigonal bipyramidal geometry for the resulting complexes has been proposed. The nitrogen atom occupies the axial site, while two methyl groups rest in equatorial positions. The antifungal activity of some of the ligands and their metal complexes has also been evaluated against different pathogenic fungi. © 1992, Taylor & Francis Group, LLC. All rights reserved.