SYNTHESIS OF SUBSTITUTED PYRIDINES BY A CYCLOADDITION ROUTE USING NITRILE OXIDES AND HOMOALLYL ALCOHOLS

被引：11
|
作者：
KANEMASA, S [1 ]
ASAI, Y [1 ]
TANAKA, J [1 ]
机构：
[1] KYUSHU UNIV, INTERDISCIPLINARY GRAD SCH ENGN, DEPT MOLEC SCI & TECHNOL, KASUGA, FUKUOKA 816, JAPAN
来源：
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN | 1991年 / 64卷 / 02期
关键词：
D O I：
10.1246/bcsj.64.375
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Cycloadditions of nitrile oxides with unprotected homoallyl alcohols, followed by Swern oxidations, lead to 5-(2-oxoalkyl)-2-isoxazolines. Subsequent Raney Ni reduction of the resulting heterocycles in ethanol in the presence of excess tetrafluoroboric acid affords substituted pyridine derivatives.
引用
收藏
页码：375 / 380
页数：6
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