Osteosarcoma of Mandible: Report of Two Cases with Review of Literature

Primary neoplasms of human skeleton are rare, accounting for 0.2% of overall human tumor burden. Osteosarcoma (OS) accounts for 15 to 35% of all primary bone tumors, in jaw bones, it is even, rarer representing 4 to 8% of all os. Peak incidence for jaw os is in 3rd to 4th decades while in long bones, it shows a bimodal age distribution. It may occur inside the bones (in the intramedullary or intracortical compartment), on the surfaces of bones and in extraosseous sites. Dental professionals may be first to detect jaw os in their initial stages. Regardless of the favorable biologic behavior, the patients of jaw os usually exhibit advanced tumor as it often goes unnoticed thus it is important for early diagnosing this lesion. Here, we report 2 cases of os with different histological subtypes (chrondroblastic and osteoblastic) and review of literature.